幻灯片 1 - Fudan University

幻灯片 1 - Fudan University

[email protected] 20/2/28 1 20/2/28

2 2020 4 4%-8% 5500 80 15 1 8 20/2/28 3

4 1 (Aretaeus)Aretaeus)) 19 (Aretaeus)Philippe Pinel) (Aretaeus)Tiberius)) (Aretaeus)Louis) )) 1896 Alloy,et al, 1996 (Aretaeus)Abraham Lincoln) 20/2/28

4 Unipolar Disorder 20/2/28 5 DSM-V

5 2 , 1 2 5% 20/2/28 6 DSM-V

20/2/28 7 20/2/28 8

Q1 Q2 Q3 Q4 Q5 Q6 Q7 Q8 20/2/28

9 20/2/28 10 DSM-V 12 7% - 18-29 60 3

- 1.5-3 26% 12% 2 Keller et al., 1984 - 1982 - 5.8% Blazer et al., 1994; Angst, 1999 17% 4% 6% 20/2/28 11 -

20 2/5 3 4/5 1 15% >2 20/2/28 12

15-19 25-29 Burke, et al, 1990 20/2/28

12 7 13 1 1. 2 2. 3. p80-83 DSM-V 20/2/28 14 2 1.

2. 3. 20/2/28 15 3 1. 2. 3. 4. 5. 6. 7. 20/2/28

16 4 1. 2. 3. 2 4. 5. 6. 7. 5% 8. 20/2/28 17

5 1. 2 + 2 2. 2 +3 4 1 2 4 3. 3 +5 1 A. B. 2 20/2/28 18

20/2/28 19 - - 46% 20% McGuffin et al. 1996

8 15 Wender et al., 1992 - 20/2/28 20 - - -

- NE 5- 5-HT NE 5-HT - 5-HT NE Rampello et al., 2000 20/2/28 21 -

- Lewinsohn et al.,1979 - 20/2/28 22 Seligman 1975 Beck 1997

- - - - - 20/2/28 23

Jenkins et al., 1998 Parkel, 1994 1. 2. 3. 4. 20/2/28 24

MAOIs 5-HT SSRIs 3 20/2/28

ECT 25 SSRI 60-65% Hirschfeld, 1999 SSRI 56% 25% Linde & Mulrow., 2002 2% 7%

20/2/28 26 psychotherapy - - - - - 20/2/28

27 NIMH Elkin et al., 1989 (51%) (30%) ( 14%) ( 16 55%) (26%) ( 57%) (19%) (50%) ( 29%) ( 20%) 16 20/2/28 28

40/10 4/10 WHO 20 70 19601975 10 (Aretaeus)McClure,2000) 2000 11.7/10 3.3/10 2/3 35 (Aretaeus)Hawton 1997)

20/2/28 29 1. 2.

3. 4. 20/2/28 30 : Q1 Q2 Q3 Q4 Q5 Q6

Q7 20/2/28 31 (Aretaeus) )&

20/2/28 32 (Aretaeus) )&

20/2/28 33

5% 20/2/28 34

1. 2. 3. 4. 20/2/28 35

02/28/20 36 220 5-

20/2/28 37

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